Senior Scientist I, Biologics Analytical R&D

Biologics Analytical R&D Scientist

The Biologics Analytical R&D (ARD) group at AbbVie plays a critical role in advancing our pipeline of next-generation biologic medicines. We develop and optimize analytical methods, provide data that drives product and process understanding, and enable the release and stability testing needed to bring innovative therapies to patients.

We are seeking a highly motivated, hands-on scientist to support early-phase programs (Discovery through Phase I) with a focus on antibodydrug conjugates (ADCs) and potential emerging modalities (e.g., LNPs, siRNA). This role is ideally suited for someone who thrives in a fast-paced, collaborative environment and wants broad exposure across techniques, modalities, and development stages.

Key Responsibilities

• Method Development & Validation: Independently design, develop, and qualify robust analytical methods (e.g., HPLC, iCIEF, CE) to support drug substance and drug product characterization, reference material qualification, and early-phase validation.
• Testing & Data Generation: Execute GMP and non-GMP testing for release and stability; deliver comprehensive data packages that inform formulation, process development, and regulatory strategy.
• Cross-Functional Collaboration: Partner closely with Drug Substance (DS), Drug Product (DP), Regulatory Affairs, QA, and PDS&T to align analytical strategy with program needs.
• Scientific Leadership: Anticipate challenges, critically evaluate new technologies, and champion innovative solutions that accelerate program progress.
• Knowledge Sharing: Author technical reports, regulatory documents, and publications; contribute to building reference standards, product control strategies, and IND/CTA submissions.
• Mentorship & Growth: Contribute to a collaborative lab environment, with opportunities to mentor junior scientists and expand expertise across multiple analytical platforms.

Qualifications

• Degree in Analytical Development, Chemistry, Biochemistry, Biology, or related discipline: BS with 10+ years industry experience, MS with 8+ years industry experience, or PhD with limited to 0 years' industry experience (new graduates considered) with relevant laboratory experience.
• Strong background in protein/biologics analytical characterization, particularly HPLC and capillary electrophoresis methods.
• Experience in method development and validation; familiarity with GMP expectations for early-phase programs.
• Demonstrated ability to work independently, manage multiple projects, and drive deliverables to completion in a fast-paced environment.
• Strong interpersonal and communication skills with a track record of cross-functional collaboration.
• Supervisory or mentoring experience preferred but not required.

Additional Information

• This is an on-site lab-based opportunity.
• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.
• This job is eligible to participate in our long-term incentive programs.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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