Executive Director, Head of Neuro-Oncology

Reporting to the Senior Vice President, Head of Oncology Franchise, the Head of Neuro-Oncology – Commercial will lead the strategy and execution of Jazz’s US Neuro-Oncology franchise, with immediate responsibility for a first-in-class therapy with significant potential to transform outcomes for patients with brain tumors. This leader will set the long-term vision for the franchise, drive commercial success across multiple functions, and ensure Jazz delivers meaningful impact for patients in neuro-oncology.

As a member of the Oncology Portfolio Cross-Functional Leadership Team, the Head of Neuro-Oncology will collaborate with counterparts in Solid Tumors and Hematology, as well as the Oncology Franchise Leader, to shape overall portfolio strategy, execution, and trade-off decisions across Jazz Oncology.

Key Responsibilities

Drive commercial success

• Lead all aspects of commercialization for a first-in-class therapy with significant potential to transform outcomes for patients with diffuse midline glioma, ensuring competitive positioning, access, and adoption.

• Develop and execute brand strategies, launch readiness, and lifecycle management plans to maximize patient impact and business growth.

• Work with the cross-functional team to explore business development opportunities in neuro-oncology

• Partner closely with R&D and Medical Affairs to integrate commercial insights into clinical development and long-term lifecycle strategies.

• Oversee operating budgets, resource allocation, and commercial performance metrics with agility and discipline.

Lead and inspire teams

• Directly oversee marketing and sales while providing matrixed leadership across Market Access, Insights & Analytics, Medical Affairs, and Patient Support Services.

• Recruit, develop, and retain top commercial talent, fostering a culture of accountability, collaboration, and innovation.

• Build organizational capability to anticipate market dynamics and deliver sustainable franchise success.

Shape external engagement

• Build strong relationships with payers, providers, advocacy organizations, and key opinion leaders in neuro-oncology.

• Champion a best-in-class patient engagement strategy that ensures the patient perspective informs decision-making.

• Represent Jazz externally as a credible and influential leader in neuro-oncology.

Contribute to portfolio leadership

• Serve as a member of the Oncology Commercial Leadership Team, aligning neuro-oncology strategy with the broader Jazz Oncology portfolio.

• Provide commercial input into portfolio planning, trade-offs, and resource prioritization.

• Collaborate with cross-functional leaders to maximize the impact of Jazz’s oncology business.

Qualifications

• 10+ years of progressive commercial leadership experience in biopharma, with significant expertise in oncology (neuro-oncology and/or rare oncology strongly preferred).

• Large team management experience preferred (10+ people)

• Demonstrated success in US P&L leadership roles with accountability for cross-functional teams (sales, marketing, market access, analytics, patient support).

• 3–5 years each of sales leadership and marketing leadership, with proven ability to launch and grow products in competitive markets.

• Deep expertise in pricing and reimbursement, HEOR, market access, and lifecycle management.

• Experience partnering with R&D and Medical Affairs to integrate commercial insights into clinical development.

• Recognized credibility with external stakeholders (KOLs, payers, advocacy groups) and strong patient and market orientation.

• Proven ability to build and inspire high-performing teams through transformation and growth.

• Strategic thinker with a hands-on, execution-driven leadership style.

• Excellent communication, influencing, and relationship-building skills at all organizational levels.

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