JobsUSA50% Asst Research Scientist/Engin
Company : University of Iowa Hospitals & Clinics
Location : Iowa City, IA, 52245
Posted Date : 15 September 2025
Job Type : Other
Category : Scientific Research & Development
Occupation : Research Scientist
Job Details
The Department of Otolaryngology is seeking a Research Assistant to conduct highly technical and specialized scientific research focused on genetic deafness (autosomal recessive and dominant nonsyndromic hearing loss), exploring phenotype-genotype relationships, novel gene discovery, gene therapy, and the contribution of genetics to age-related hearing loss. This individual will evaluate genetic data to determine genotype-phenotype correlations and develop methodology to identify novel disease-causing loci. Additionally, they will independently secure funding, conduct research experiments, analyze data, and disseminate findings through publications and presentations.
Percent Time: 50%
Duties to include:
Experiments, Simulations, Modeling or Theoretical Investigations:
- Interrogate genetic regions of interest related to autosomal recessive and dominant non-syndromic hearing loss through methods such as in vivo and molecular experiments, including cell culture, immunohistochemistry, and viral vector injections in rodent models.
- Collect and evaluate data integrity and relevance to research questions.
- Evaluate data to establish relevance to the problem or problems being evaluated.
- Define outstanding research problems and contribute to protocol development
- Work independently on research tasks with oversight by Principal Investigator (PI).
- Contribute to documentation of equipment and procedures.
- Develop new protocols for research and obtain support for new and/or continuing research activities.
- Analyze data for relevance and data integrity.
- Perform basic data analysis techniques.
- Compare results of scientific investigations to previously published work.
- Prepare research results for publication in reports, papers, journals, books and other media.
- Prepare seminars, discussions and lectures for dissemination of knowledge and results of research.
- Represent the entire research group at professional meetings.
- Maintain liaison with sponsoring agencies and organizations as well as with other research and educational institutions.
- Manage all or part of a research project including staff selection, assignment and scheduling, monitoring of project funds, coordination of data generation and analysis and identification, acquisition and use of equipment and facilities.
- Participate in determining research priorities and planning programs of research.
- Maintain effective working relationships with faculty, staff, students and the public.
- Demonstrate respect for all members of the University community in the course of performing one's duties and in response to administrators, supervisors, coworkers and customers.
- Welcome the richness of talent from a diverse workforce and recognizes that diversity brings stimulation, challenge and energy that contribute to the productive and effective workplace.
- Represent the interests of the University and of unit leadership in the use of resources to meet service and productivity demands within unit goals and budgets; strives to promote continual processes and quality improvement.
- Seek opportunities to enhance one's own professional knowledge, skills and abilities as they relate to one's current position and/or to prepare for potential future roles and overall career development.
- Train investigators and support staff and conduct continuing education.
- Mentor graduate students, medical residents on research rotations and research assistants working in the lab or collaborating from other labs.
- Provide functional and/or administrative supervision for staff.
- Supervise adherence to safety and compliance guidelines when necessary.
Required Qualifications:
- Academic knowledge of a discipline generally associated with a Doctoral degree in molecular biology, genetics or an equivalent professional degree, i.e. MD, DDS or DVM. In addition, the person will have demonstrated the ability to plan and execute a research study through some progressively independent research work.
- Minimum of 3 years of post-doctoral relevant laboratory experience in hearing genetics or related field is required.
- Strong working knowledge of in vivo experimental procedures in rodent (mouse): such as bacteria and cell culture.
- Strong working knowledge of hearing testing in rodent, such as: Auditory Brainstem Response (ABR) and Distortion Product Otoacoustic Emissions (DPOAE), noise overexposure.
- Strong working knowledge of mouse inner ear surgery, relative to viral vector injection
- Strong working knowledge of the middle and inner ear anatomy and proficiency in harvesting, dissecting and preparing cochlear samples.
- Strong working knowledge of cochlear morphology and sample preparation for various microscopy technics: such as Scanning and Transmission Electron Microscopy (SEM, TEM), confocal and light imaging.
- Strong working knowledge of molecular evaluation technics such as: PCR, RTqPCR, western blotting, Co-IP, immunofluorescence and of the associated equipment.
- Experience genetic analysis technologies and analytical strategies.
- Effective interpersonal skills required as well as written and oral communication and presentation skills.
- Proficient computer skills including Graph pad Prism, Adobe illustrator, Photoshop, ImageJ as well as working knowledge statistical analysis.
- Strong working knowledge of plasmid construction.
- Knowledge of University of Iowa Policies and Procedures.
- Supervisory experience is highly desirable.
In order to be considered for an interview, applicants must upload the following documents and mark them as a "Relevant File" to the submission:
- Resume
- Cover Letter
For additional questions, please contact .
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