Sr. Research Scientist

Sr. Research Scientist

Candidate will be responsible for performing in vitro studies for cancer drug discovery programs. This includes the development of relevant preclinical model systems for the identification and validation of novel therapeutic targets. The successful candidate is able to work with minimal supervision in most molecular and cellular biology techniques and demonstrates an understanding of cancer biology. Experience with oncogenic signaling pathways and targeted therapies is an advantage. The candidate is expected to work with their supervisor to design and execute a research plan that will answer critical questions about compounds and targets under evaluation.

• Design, execute and interpret in vitro pharmacology experiments to guide compound SAR development and explore therapeutic potential of drug targets
• Apply chemical and genetic tools as well as state-of-art technologies to interrogate cancer biology and understand the mechanism of actions of novel targets
• Experienced in protein analysis techniques such as Western Blot, ELISA, MSD, HTRF
• Familiar with small molecule drug screening and cell-based assay development.
• Identify or develop appropriate in vitro model systems to answer key biological or pharmacological questions
• Experience in advanced cell culture techniques, including three-dimensional (3-D) cell culture systems, co-culture systems and organoid culture systems
• Ability to maintain accurate and detailed records of experiments, evaluate data, prepare reports and presentations for internal meetings in a timely manner
• Work collaboratively across multiple functional groups to achieve drug discovery goals
• Communicate key findings to leadership team at internal meetings to help decision making

The pay range for this position is $22.00 - $25.00/hr.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:

• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave)

This is a fully onsite position in Philadelphia,PA.

This position is anticipated to close on Sep 25, 2025.