Sr Manager, Hypercell, Operational Excellence Lead

Operational Excellence Lead

Working with Us Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services, and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Position Summary

The Hypercell team is focused on transforming cell therapy operations by streamlining supporting processes through digital, automation, and AI-driven solutions. We are seeking an Operational Excellence Lead to drive continuous improvement, standardization, and efficiency across the cell therapy network. This role will be instrumental in identifying and eliminating waste, improving process reliability, and enabling scalable operations through data-driven insights and cross-functional collaboration.

Key Responsibilities

• Support the Hypercell team to define transformative processes, applying Lean, Six Sigma, and other continuous improvement methodologies to existing business processes to drive innovation.
• Partner with process engineering, quality, and operations teams to identify and implement opportunities for simplification, automation, and standardization.
• Develop and maintain performance metrics, dashboards, and reporting tools to monitor progress and drive accountability.
• Facilitate activities across Hypercell including value stream mapping, lean processing, and Kaizen events to address operational pain points and unlock efficiencies.
• Support the deployment of AI-facing tools and digital solutions that enhance decision-making and reduce manual effort.
• Collaborate with site and global stakeholders to harmonize best practices and ensure alignment with broader Cell Therapy and Global Product Supply strategies.
• Champion a culture of continuous improvement, operational discipline, and innovation across the team.
• Author and contribute to documentation including SOPs, training materials, and change control packages.

Qualifications & Experience

• Bachelor's or Master's degree in Engineering, Life Sciences, Business, or related field.
• 5+ years of experience in operational excellence, manufacturing, or process improvement roles, preferably in cell therapy, biologics, or regulated biopharma environments.
• Strong knowledge of Lean, Six Sigma, and other continuous improvement frameworks; certification preferred.
• Experience with digital transformation, automation, and data analytics tools.
• Proven ability to lead cross-functional teams and drive measurable results.
• Excellent communication, facilitation, and stakeholder engagement skills.

Preferred Qualifications

• Familiarity with GMP manufacturing and regulatory requirements for advanced therapies.
• Experience supporting digital and AI initiatives in a manufacturing or technical operations context.
• Ability to translate complex operational challenges into actionable improvement plans.

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.