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Bioinformatics Scientist

Guidehouse

Company : Guidehouse

Location : Bethesda, MD, 20811

Posted Date : 5 October 2025

Job Type : Other

Category : Scientific Research & Development

Occupation : Scientist

Job Details

Overview

Join to apply for the Bioinformatics Scientist role at Guidehouse .

Job Family: Scientific Research & Analysis (Digital)

Travel Required: Up to 25%

Clearance Required: Ability to Obtain Public Trust

What You Will Do

  • Utilize computer simulation expertise such as molecular dynamic and monte carlo simulations to solve protein structures’ dynamics and mechanism of protein-protein interaction.
  • Develop and apply in silico tools to design vaccine and therapeutic products against diverse pathogens, including HIV-1, Influenza, or Malaria.
  • Develop methods to study vaccin-elicited immune responses, including antibodies’ sequence and structural analysis.
  • Develop and apply custom-made AI/ML tools to analyze vaccine outcomes.
  • Serve as expert to identify critical/biological findings of experimental data and collaborate with other scientists.
  • Utilize High performance computing (HPC) to bring the state-of-the-art techniques such as machine learning, artificial intelligence, deep learning to vaccine target protein design.
  • Co-lead on projects, including (but not limited to) HIV-1 Malaria, Influenza and Lassa) and coordinate with scientists from other organizations or institutions involved in similar or related research projects.
  • Provide scientific expertise to facilitate protein and vaccine design.
  • Mentor interns and postbaccalaureate scientists.
  • Publish the findings and analysis in peer-reviewed journals.

What You Will Need

  • PhD in Computational Biology/Chemistry or a related field is required.
  • 2-3 years of postdoctoral experience is required.
  • Utilize computer simulation expertise such as molecular dynamic and monte carlo simulations to solve protein structures’ dynamics and mechanism of protein-protein interaction.

What Would Be Nice To Have

  • Demonstrated ability to work on multiple projects.
  • Strong communications skills, both oral and written.

What We Offer

  • The annual salary range for this position is $98,000.00-$163,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.
  • Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
  • Benefits Include
  • Medical, Rx, Dental & Vision Insurance
  • Personal and Family Sick Time & Company Paid Holidays
  • Parental Leave
  • 401(k) Retirement Plan
  • Group Term Life and Travel Assistance
  • Voluntary Life and AD&D Insurance
  • Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
  • Transit and Parking Commuter Benefits
  • Short-Term & Long-Term Disability
  • Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
  • Employee Referral Program
  • Corporate Sponsored Events & Community Outreach
  • Care.com annual membership
  • Employee Assistance Program
  • Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
  • Position may be eligible for a discretionary variable incentive bonus

About Guidehouse

Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation. Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco. If you require an accommodation, contact Guidehouse Recruiting at or All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation. All recruitment communications will come from Guidehouse email domains including @guidehouse.com or Guidehouse does not charge fees from applicants or require money transfers at any stage of the recruitment process. If you suspect a scam, report to Guidehouse’s Ethics Hotline. Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse.

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