2026 Computational Data Scientist Intern (PhD)

Abbvie Genomics Research Center Internship

Envision spending your summer working with energetic colleagues and inspirational leaders, all while gaining world-class experience in one of the most dynamic organizations in the pharmaceutical industry. This is a reality for AbbVie Interns.

The Genomics Research Center (GRC) plays an integral role towards the goal of developing world class genetics and genomics research, focusing on finding the right targets and helping us better understand not only human disease biology but also the behavior of and response to our drugs in clinical trials. Within the GRC, the Human Genetics (HG) team assists in the identification and characterization of underlying genetic factors associated with diseases and aims to understand the mechanism of drug response through quantitative analyses. Major focuses include new target discovery via genetic evidence from population-based studies, large biobanks, molecular phenotypes, and deeper investigation of targets through functional genomics. This internship will focus on comparing and leveraging variant annotation tools (e.g., VEP, FAVOR, RegulomeDB, SpliceAI, AlphaGenome) and databases to annotate variants from real sequencing datasets, with the goal of prioritizing those most likely to have functional impact in association studies.

Key responsibilities include:

• Survey and compare major variant annotation tools (e.g., VEP, SnpEff, ANNOVAR).
• Compare the gene and transcript lists of humans in RefSeq and Ensembl/GENCODE.
• Explore and integrate multi-source annotations (e.g., ClinVar, HGMD, splice-disrupting variants in SpliceAI, functional scores in FAVOR, AlphaMissense & AlphaGenome, and regulatory features).
• Annotate the variants in a WGS project using selected tools and support/conduct association analysis.

Qualifications:

Minimum Qualifications

• Currently enrolled in university, pursuing a PhD in Genome sciences, Bioinformatics, Biostatistics, Human genetics, Computer Science or other related fields
• Must be enrolled in university for at least one semester following the internship
• Expected graduation date between December 2026 July 2027
• Proficient in programming languages (R or Python)
• Strong written and verbal communication skills
• Self-directed and able to work with minimal supervision

Preferred Qualifications

• Have experience performing variant annotation and prioritizing variants based on their annotations
• Strong quantitative and analytical skills
• Energetic and eager to tackle new projects and generate new ideas

Benefits and Amenities

• Competitive pay
• Relocation support for eligible students
• Select wellness benefits and paid holiday / sick time

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.