Senior Scientist/Principal Scientist, Oncology Translational Development

Working with Us

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Translational Medicine at BMS

Translational Medicine is a department within the Research organization that facilitates the transition of drug candidates from early to late-stage clinical development, their approval and life cycle management. Early-stage translational development activities enable rational determination of dose-schedule and responsive patient populations, based on deep understanding of drug mechanism of action and disease segments. Late-stage translational development activities build upon the early work, additionally exploring mechanisms of resistance, rational drug combinations and product differentiation. The late-stage translational development function is responsible for the development of translational strategies to support the development, and maximize the potential, of BMS’s therapies post-clinical proof-of-concept, including registrations and life‑cycle management. Translational disease strategies in solid tumor oncology are derived from long term investments in developing data and deep expertise in disease biology, patient segmentation and therapeutic resistance to inform science-driven strategies for the development of the oncology pipeline.

Summary

Reporting to the Oncology Disease Head (Breast Cancer) in Translational Development, the incumbent will be part of the Translational Development team and will help develop translational disease strategies in Breast cancer (BrCa) across multiple asset programs in early and late stage development for approval or life‑cycle management in the BMS pipeline. Key responsibility of this role is to effectively collaborate with a cross-functional team of asset scientists with deep disease, drug development and business knowledge to help drive an overall translational strategy, working closely with discovery and early development teams, late clinical development as well as with our team of laboratory scientists.

Position Description

• Develops and executes translational disease strategy in BrCa with deep disease expertise
• Leads and oversees execution of disease strategy including patient selection strategies
• Serves as scientific expert, generating novel hypotheses for actionable biology based on novel discoveries integrating disease work with literature and deep BrCa biology expertise
• Manages cross-functional disease project teams with key interfaces in IT, bioinformatics, data sciences, biostatistics, external collaborators, contractors, and other disease strategy leads and asset leads
• Maintains relationship with physician scientists for identifying new opportunities and gaining disease insights
• Identifies needs, gaps and translational disease questions and applies knowledge across all BMS BrCa portfolio assets
• Leads collaborations with academia and industry partners to identify biobanks, clinical trials and existing databases to collate multi-parameter genomic, immune and clinical datasets to mine for novel biomarkers of unmet‑need patients in conjunction with computational biologists, data scientists and statisticians
• Collaborates and guides bioinformatics partners on biological questions to deliver biomarkers and biological understanding from whole transcriptome, whole exome, and/or whole genome data, immune profile and single-cell data to support drug discovery and development in the BrCa space
• Manages relationships with key internal stakeholders including Regulatory, Clinical, Commercial, Medical Affairs & Communications and external collaborators to develop translational analysis plans, timelines and communicate analysis results
• Represents the Solid Tumor Translational Development function at internal meetings and provides domain knowledge and disease expertise to cross-functional teams
• Directs and supports publications in high quality scientific, technical or medical journals

Qualifications

• PhD degree in a relevant field (e.g. molecular biology, cancer biology, human genetics, immunology)
• Senior Scientist: 3+ years post‑PhD experience with demonstrated scientific leadership in integrating, analyzing and interpreting multimodal translational data in an academic and/or industry setting
• Principal Scientist: 5+ years post‑PhD experience with demonstrated scientific leadership in integrating, analyzing and interpreting multimodal translational data in an academic and/or industry setting
• Strong background in human cancer genetics, tumor biology & immunology, genomics/multi‑omics with deep understanding of tumor‑intrinsic and tumor‑extrinsic mechanisms driving cancer development and therapeutic resistance
• Extensive knowledge of high‑content biomarker platforms and good understanding of current clinical practice in BrCa
• Ability to work in a fast‑paced environment with rapidly changing and competing priorities and ambiguity
• Strong team player with the ability to work in cross‑functional teams; excellent communication and collaboration skills
• Prior experience with clinical trials preferred
• Strong track record of high‑quality scientific publications in relevant fields

Compensation Overview

Senior Scientist: $112,000‑$140,000 plus incentive cash and stock opportunities (based on eligibility). Principal Scientist: $140,000‑$165,000 plus incentive cash and stock opportunities (based on eligibility). Final, individual compensation will be decided based on demonstrated experience.

Benefit offerings are subject to the terms and conditions of the applicable plans in effect and may include medical, pharmacy, dental and vision care; wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP); financial well‑being resources and a 401(K); and work‑life programs including paid national holidays, optional holidays, up to 120 hours of paid vacation, paid volunteer days, sick time, and summer hours flexibility. Parental, caregiver, bereavement and military leave; family care services such as adoption and surrogacy reimbursement and fertility/infertility benefits; and other perks including tuition reimbursement and a recognition program.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as “Transforming patients’ lives through science™”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On‑site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site‑essential, site‑by‑design, field‑based and remote‑by‑design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role.

Site‑essential roles require 100% of shifts onsite. Site‑by‑design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For field‑based and remote‑by‑design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support. Applicants can request a reasonable accommodation before accepting a job offer. If you require an adjustment in completing this application or in any part of the recruitment process, direct inquiries to Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS recommends that all employees be fully vaccinated for Covid‑19 and keep up to date with boosters. BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Eligibility

#LI‑Hybrid

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.