Senior Associate Scientist (Genomic Characterization/Cell Therapy)

Senior Associate Scientist, Drug Safety Evaluation Cell Therapy

At Bristol Myers Squibb (BMS) we're on the cutting edge of cellular immunotherapy, harnessing the power of Chimeric Antigen Receptor (CAR) and T Cell Receptor (TCR) technologies to revolutionize cancer treatment. Our mission is bold: to develop cell therapies that overcome tumors resistant to current approaches and bring hope to patients worldwide.

The Drug Safety Evaluation Cell Therapy team in Seattle is seeking a passionate, creative, and driven research scientist to help shape the future of cell therapy safety. If you thrive in a fast-paced, collaborative environment and are excited by the challenge of pioneering new platforms and technologies, we want to hear from you!

Why Join Us?

• Be at the forefront of scientific innovation, working with world-class experts to develop therapies that could change the standard of care for cancer.
• Play a role in advancing early cell therapy programs and establishing preclinical safety strategies for next-generation CAR and TCR targets.
• Make an impact by developing and refining in vitro model systems that address critical clinical and scientific risks, with a focus on genomic integrity and in vitro biology.

What You'll Do:

• Collaborate with talented colleagues to evaluate new CAR and TCR T-cell products and tackle toxicology challenges in cutting-edge therapeutic strategies, including gene editing and cell engineering.
• Design and execute sophisticated experiments to predict on- and off-target risks, developing innovative cell and tissue-based in vitro models and molecular assays.
• Build deep expertise in engineered T-cell therapies, focusing on preclinical safety evaluation and contributing to the advancement of transformative medicines.
• Communicate your findings clearly and effectively to project teams and collaborators, preparing impactful presentations and technical reports.
• Deliver on short-term project goals while driving innovation that will shape the future of safety evaluation for CAR and TCR T-cell modalities.

Position Details:

• The role is primarily laboratory-based within our Nonclinical R&D team in Seattle.

Are You Ready to Make a Difference?

If you have expertise in immunology and molecular biology, a passion for scientific discovery, and a desire to help bring life-changing therapies to patients, apply today and join us in our mission to transform cancer care.

Qualifications & Experience

• B.S., M.S. or Ph.D. in immunology, bioengineering, biochemistry, molecular biology, toxicology, or related discipline, with at least 4 (B.S.), 2 (M.S.) years of relevant work experience preferred.
• Scientific expertise evidenced by publication record and/or presentations
• Excellent laboratory-based skills in cell and molecular biology
• Proficiency in general laboratory bench skills such as multi-color flow cytometry, cell imaging, ELISAs, Luminex, Mesoscale, and western blotting
• Fluorescence and/or confocal microscopy, live cell imaging and analysis is desirable
• Proficiency in molecular biology; experience with genome editing methodologies, gene expression analysis is preferred
• Culture of primary and immortalized mammalian cells and cell line development
• Analytical methods for functional characterization of T cells (activation, cytotoxicity, cytokine secretion, proliferation etc.)

Compensation Overview: Seattle - WA: $88,430 - $107,151

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit careers.bms.com/life-at-bms/. Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as "Transforming patients' lives through science ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/.

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