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Scientist

Guidehouse

Company : Guidehouse

Location : Gaithersburg, MD, 20877

Posted Date : 12 October 2025

Job Type : Other

Category : Scientific Research & Development

Occupation : Scientist

Job Details

Research Analyst (Digital)

Coordinate and execute formulation and stability studies within a development team, including internal and interdepartmental coordination of activities as well as collation and interpretation of study data, under direction of a Formulation Scientist/Senior Scientist.

Write and review formulation, stability, and method development study protocols under direction of a Formulation Scientist/Senior Scientist.

Independently generate and analyze samples using both standard and advanced study specific analytical methods.

Independently analyze and collate analytical data.

Interpret analytical data with an understanding of protein/vaccine structure and stability concepts, and elements of the effects of solution components on stability.

Develop assays for vaccine and biotherapeutic characterization, including providing input into study design, under direction of a Formulation Scientist/Senior Scientist.

Provide technical guidance and training to formulation team members.

Write and review technical reports and protocols documenting formulation, stability, and method development studies.

Present data in small group, department, and conference settings.

Obtain information on new scientific advances in the field and new technologies, as required to for VRC programs.

Oversee external service and execute routine maintenance and troubleshooting for one or more pieces of laboratory instrumentation.

Serve as Subject Matter Expert for one or more analytical and/or theoretical areas relevant to the formulation development program.

B.S. in Chemistry, Biochemistry, Chemical Engineering, or a related discipline.

4 years (minimum) industry, government or equivalent experience in protein formulation or a related field.

Minimum of TWO (2) years industry, government or equivalent experience in protein formulation or a related field.

Experience with study coordination and execution in one or more of the following areas: protein/vaccine formulation, protein/vaccine stability, protein/vaccine pre-formulation or related biophysical characterization/development.

Hands-on experience, including data analysis and basic theoretical knowledge, with three or more of the following techniques: UV-visible, fluorescence, Circular Dichroism and/or IR spectroscopy; Differential Scanning Calorimetry; Particle characterization (light scattering, subvisible particle analysis, HIAC, and/or MFI).

Strong knowledge of protein chemistry and biophysical properties of proteins.

Knowledge of standard biophysical and bioanalytical methods and underlying theory.

Experience with data analysis using standard and specialized software platforms (JMP, Origin, GRAMS, Prism, SigmaPlot, etc.).

Strong time management skills and experience balancing multiple projects.

Strong written, oral, and visual communication skills.

Ability to work independently

Proficiency with Microsoft Word, PowerPoint, or other equivalent software suites.

The annual salary range for this position is $74,000.00-$124,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

  • Medical, Rx, Dental & Vision Insurance
  • Personal and Family Sick Time & Company Paid Holidays
  • Parental Leave
  • 401(k) Retirement Plan
  • Group Term Life and Travel Assistance
  • Voluntary Life and AD&D Insurance
  • Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
  • Transit and Parking Commuter Benefits
  • Short-Term & Long-Term Disability
  • Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
  • Employee Referral Program
  • Corporate Sponsored Events & Community Outreach
  • Care.com annual membership
  • Employee Assistance Program
  • Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
  • Position may be eligible for a discretionary variable incentive bonus

Guidehouse is an Equal Opportunity EmployerProtected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

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