Principal Scientist Transporters

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .

Role Description:

Bristol Myers Squibb Drug Metabolism and Pharmacokinetics (DMPK) Department seeks a passionate Principal Scientist to provide scientific leadership and mentorship within our Transporter Group. The Transporter Group is a center of excellence serving to understand the roles of transporters in drug ADME, efficacy and toxicity and to de-risk the potential for transporter mediated DDIs. The group supports the BMS portfolio through all stages of discovery and development with stage-appropriate, hypothesis driven, in vitro and in vivo transporter assessments; applying mechanism-based approaches to the quantitative translation of pre-clinical in vitro and in vivo data to clinical findings.

Key Responsibilities:

• Provide scientific oversight and mentorship within the Transporter Group, fostering a mindset of scientific rigor, critical thinking, and creative problem-solving.
• Support program teams by proactively identifying transporter-mediated ADME risks; designing, executing, and interpreting data from critical experiments. Effectively communicate findings to teams, prepare and review regulatory source reports.
• Troubleshoot and optimize in vitro transporter assays and identify and implement novel experimental strategies to enhance clinical translation of pre-clinical data.
• Contribute to the strategic direction of the Transporter Group, expanding our science and staying current with literature. Publish and present at internal and external meetings.

Qualifications:

• Ph.D. in biology, toxicology, pharmacology, or related major, with 4+ years of experience in the ADMET field, or Master’s degree with 6+ years relevant ADMET experience.
• Demonstrated ability to mentor and grow team members.
• In-depth expertise in the field of drug transporters, with understanding of ADMET principles.
• Extensive hands-on experience with in vitro drug transporter assays, proven ability in independent experimental design and analysis, with exceptional critical thinking and problem-solving abilities.
• Excellent written and oral communication skills.

The starting compensation for this job is a range from $138,850 - $168,300, plus incentive cash and stockopportunities (based on eligibility).

The starting pay rate takes into