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Associate Director, Sr Principal Systems Engineer

Bristol Myers Squibb

Company : Bristol Myers Squibb

Location : Cambridge, MA

Posted Date : 18 October 2025

Job Type : Full Time

Category : Industrial Engineering

Occupation : Systems Engineer

Job Details

Working with Us

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .

Summary:

Bristol Myers Squibb is looking for an experienced Sr Principal Systems Engineer in HPC/AI infrastructure to work with our technology teams and various stakeholders to design, manage, and support cutting-edge HPC/AI infrastructure platforms to serve our community of researchers and scientists, who are using Machine Learning, Deep Learning, and High-Performance Computing every day to make groundbreaking discoveries.

Collaborating with cross functional teams within BMS, the systems engineer would work our teams to define and execute our HPC/AI roadmap for both on-premises datacenters and in the cloud, provide guidance and technical expertise to senior research leaders and scientists, and work to build out standards and best practice design principles to guide BMS' future roadmap.

Key areas of the role require strong knowledge and expertise in:

  • Software/Hardware Optimization, such as performance tuning for bespoke hardware, code refactoring, accelerated ML toolkit and libraries such as CUDA, and continuous integration of codes and ML models.

  • Development Tools and Environment, such as Git, Linux and python package management , pytorch lightning, containers, and Kubernetes.

  • Job/Scheduler Orchestration and Integration, knowledgeable in automating and integrating machine learning jobs with major resource schedulers such as SLURM, Grid Engine, AWS Batch, and Parallel Cluster to maximize throughput, performance, utilization, efficiency, and cost effectiveness for ML/AI training and prediction.

  • Datacenter/Colocation Operations, such as physical installation, networking or bespoke network fabrics, understanding of power/cooling, etc. are strongly preferred.

  • Vendor Outreach , ability to partner with leading vendors or partners to explore, experiment, and pilot proof-of-concept studies to help bring in, or deliver leading-edge, differentiating capabilities for BMS Research

Requirements:

  • Strong experience working with and supporting HPC users, including scientists, data scientists, and/or developers

  • Strong working experience with container runtimes and container orchestration platforms, including Kubernetes, Docker, and/or Singularity

  • Strong operational, architecture, and troubleshooting experience with cluster managers and schedulers, ideally Slurm but experience with other HPC schedulers should be acceptable.

  • Linux systems management and configuration management in an HPC environment

  • Expert troubleshooting skills with open source frameworks and libraries

  • Experience working with the NVIDIA software ecosystem and GPU-powered systems for Machine Learning and Deep Learning workloads (preferred)

  • Experience working with Deep Learning frameworks, libraries, and pipelines, either directly as a user or supporting researcher and/or data science users (preferred)

  • Experience working with parallel file systems for data storage strategies for large clusters (preferred)

  • Working knowledge of GPU profiling techniques (preferred)

The starting compensation for this job is a range from $170,000 - $195,000, plus incentive cash and stock opportunities (based on eligibility).

The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed.

Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:

Cambridge Crossing: $186,070 - $225,467

Princeton - NJ - US: $169,150 - $204,970

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as Transforming patients' lives through science , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to . Visit careers.bms.com/ ( eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Company: Bristol-Myers Squibb

Req Number: R

Updated: :05:51.886 UTC

Location: Princeton-NJ

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.

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