Advisor - RNA Biologist

Job Details
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
At Lilly's Biotechnology Center in San Diego, we discover medicines that address significant unmet needs by integrating biology with innovative scientific capabilities in RNA and computational sciences. We collaborate with colleagues in both the discovery and development organizations, including scientists in therapeutic area biology, biomolecule formulation and developability, ADME, Toxicology, PK/PD, Statistics, Computational Sciences, clinical development, and more.
We are seeking a highly motivated scientist to join our Genetic Medicine team. The successful candidate will have a strong research track record in mRNA regulation and NGS applications. The scientist will collaborate with multidisciplinary teams across key Lilly therapeutic areas (e.g. neuroscience, diabetes, immunology) to perform experiments to aid development of RNA oligonucleotide drug candidates for the next generation of RNA therapies.
Key responsibilities include:

• Design and develop mRNA reporters and engineered cell lines for massively parallel reporter assays.
• Routinely perform cell transfection, mRNA purification, and mRNA quantitation
• Prepare samples for NGS applications (RNA-seq, PolyA-seq, 5'RACE)
• Independently problem-solve in the laboratory setting to overcome challenges and improve upon existing workflows
• Maintain laboratory equipment and manage laboratory inventory/consumables.
• Visualize, summarize, and present results to team members,
• Work with CROs to execute research studies

Basic Qualifications:

• PhD in molecular biology, biology, or related scientific field with experience in post-transcriptional regulation
• 3+ years of relevant work experience

Additional Skills/Preferences:

• Prior experience with RNA profiling and NGS tools (CLIP, RNA-seq, Ribo-seq), massively parallel reporter assays, cell-based high throughput screens
• Prior experience with cell-line engineering and recombinant nucleic acid methodologies
• Prior experience working with CROs
• Deep subject matter expertise in mRNA regulation, RNA binding proteins, NGS-based approaches, cell-line engineering, mRNA reporter systems, high throughput screens, transcriptome profiling
• Prior project management experience
• Excellent communication (oral/written), organization, interpersonal skills, and team-player mindset

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$133,500 - $217,800
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Company
Science has been our calling from the beginning. Colonel Eli Lilly founded the company in 1876 and charged employees to "take what you find here and make it better and better." More than 147 years later, we remain committed to his vision through every aspect of our business and the people we serve, starting with discovering the best treatments for those who take our medicines and extending to health care professionals, employees and the communities in which we live. Moreover, you can also count on the team at Lilly to be incredibly civic-minded, supporting our communities through philanthropy, volunteerism, and a creative and innovative can-do spirit.
Company info
Location 893 S Delaware St
Indianapolis
Indiana
46285
United States
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