Senior Scientist, Oncology Discovery Biology

Working at Bristol Myers Squibb

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Oncology Thematic Research Center

The Oncology Thematic Research Center at BMS is a key research and early development engine, responsible for the discovery and development of novel oncology therapeutics for patients. Centered at our state-of-the-art research sites in Cambridge and Seattle, scientists focus on novel targets and pathways for tumors that are refractory to current therapies. With a deep understanding of the causal human biology, we are able to leverage our multiple modality platforms to best match the modality to the mechanism and desired outcome. We are a fully integrated drug discovery through translational and early clinical development organization which exploits state-of-the-art in vitro, in vivo and ex-vivo models of Cancer biology and Immuno-oncology to identify and validate targets. We partner closely with colleagues in Translational Medicine, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient enrichment hypotheses to enable efficient decision making in early clinical trials. We are optimally positioned to complement the world-class translational expertise, biology and leading academic research centers in the area.

Position Summary

We are seeking an innovative and motivated immunologist to advance our portfolio of pioneering T cell engager therapeutics to treat cancers. The successful candidate will join the Discovery Biology Team within the Oncology Thematic Research Center at Bristol Myers Squibb in Seattle, WA. The qualified candidate will provide expertise in immunology and will join a multidisciplinary, groundbreaking team driving projects from discovery through IND. Using their knowledge in T cell immunology, the candidate will have the opportunity to identify and validate novel targets and design novel assay systems to enable next-generation engager cancer therapeutics. This scientist will work in a highly collaborative, dynamic, fast-paced environment involving multiple teams across the company.

Position Responsibilities

In the role as a Senior Scientist within Discovery Biology, the ideal candidate will:

• Identify and validate novel targets for development of T cell engagers.
• Independently design, develop and execute novel in vitro and ex vivo cell-based assays/models to evaluate the efficacy and specificity of T cell engagers.
• Apply knowledge of T cell biology to develop next-generation T cell engagers with improved efficacy and safety profiles.
• Design and implement critical studies required to drive hypothesis-driven research.
• Collaborate across multiple projects / roles in a matrixed environment.
• Present complex concepts to a range of audiences including governance and full team project meetings.
• Utilize excellent communication and interpersonal skills to drive collaboration and alignment with key stakeholders.

Experience

Basic Qualifications:

• Bachelor's Degree
• 6+ years of relevant academic and/or industry experience

• Or
• Master's Degree
• 4+ years of relevant academic and/or industry experience

• Or
• Ph.D. or equivalent advanced degree in the Life Sciences
• 2+ years of relevant academic and/or industry experience

Preferred Qualifications

• Ph.D. or equivalent advanced degree in immunology, immuno-oncology, tumor immunology, or a related field
• 2+ years of relevant academic and/or industry experience
• Knowledge of T cell biology and relevant in vitro assay systems and experience with transformed tumor cells is strongly preferred.
• Experience with technologies typically employed to engineer cell lines and assess immune cell function including but not limited to subset of CRISPR, RNAi, Luminex, MSD, IncuCyte-based assays, multi-parameter flow cytometry, T cell activation assays, T cell proliferation assays, imaging technologies.
• Demonstration of hypothesis-driven, in-depth, innovative thinking and experimentation.
• Self-motivated and focused with project management-oriented thinking; able to work on multiple projects in a matrix environment.
• Ability to communicate well with peers, supervisors, and governance committees.
• Strong problem-solving skills and understanding of complex scientific principles.
• Requires strong organizational skills to ensure thorough and timely documentation of experiments, and preparation of data for compiling reports for both internal and external documents.
• Experience with antibody drug discovery and target identification/validation is an advantage.

Compensation

The starting compensation for this job is a range from $131,590 - $159,500, plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Career Site.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as "Transforming patients' lives through science ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid