Senior Scientist I, Immunosafety/Immunogenicity

Senior Scientist I

The Senior Scientist I will evaluate the immunogenic and immunosafety risk potential of candidate therapeutic large molecules in vitro assays. Author preclinical reports to support filing documentation including data aggregation and QC evaluation.

Responsibilities

• Execution of in vitro immunogenicity and immunosafety platform for risk assessment including soluble and slide phase cytokine release, T cell proliferation, and cell death bioassays and assessing effector functions of biologic drug candidates.
• Represent IVIS team on project meetings and designing & coordinating in vitro immunosafety and immunogenicity studies of drug candidates.
• Author publication, presentations, and/or regulatory documents.

Qualifications

• Bachelor's Degree and typically 10 years of experience OR Master's Degree and typically 8 years of experience OR PhD and no experience.
• Degree in Biological Sciences, Cellular Immunology, or related field.
• Extensive experience with multicolor flow cytometry panel design, BD LSRFortessa instrument operation, BD FACSDive and FlowJo software, and flow cytometry data analysis.
• Proven track record of successfully handling human samples, isolating cell subsets, and executing bioassays.
• Experience with report generation for the support of IND documentation a plus.
• Excellent interpersonal and oral/written communication skills.
• Results-oriented work ethic and a positive "can-do" attitude with a strong sense of urgency and self-motivated desire to achieve common business goals.
• Demonstrated ability to collaborate effectively in a dynamic, cross-functional matrix environment.

Additional Information

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.
• This job is eligible to participate in our long-term incentive programs

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.