Scientist II

Exploratory Biologics Scientist

We are currently seeking a highly motivated and passionate scientist to join the Exploratory Biologics group within the Immunology Discovery Department in Cambridge, MA. The successful candidate will contribute to the discovery of targeted therapeutic molecules by evaluating novel protein degraders through functional cellular assays leveraging strong expertise in cell biology and biochemistry. This position provides an exciting opportunity for a talented scientist to grow their career in a dynamic innovative and multi-disciplinary environment at the interface of basic research and early drug discovery. The scientist will be responsible for conceptualizing, designing, and executing experiments, generating and characterizing therapeutic reagents, and conducting data analysis to advance innovative drug discovery programs. The ideal candidate should be independent and collaborative with excellent technical, written, and oral communication skills and a strong drive to contribute to breakthrough research in immunology and biologics.

Qualifications and requirements:

• Bachelors or Masters degree in Immunology, Cell Biology, or a related Biological Sciences field with 3-5 years of relevant hands-on experience.
• Extensive experience in in vitro human cell culture including various immune cell types with proven ability in cell-based assay development.
• Proficiency in multi-color flow cytometry including instrument operation e.g. BD Canto MACSQuant and independent data analysis using FlowJo or equivalent software.
• Background in cell biology and biochemistry techniques such as ELISA/MSD, Western blotting Wes/Jess, and confocal microscopy.
• Demonstrated ability to design, plan, and execute well-controlled in vitro experiments using novel research tools or reagents.
• Hands-on experience with protein-protein interactions, degradation pathways, and lysosomal biology is highly desirable.
• Prior research experience with cutting-edge protein degradation technologies e.g. PROTACs, LYTACs or related modalities is strongly preferred.
• Self-motivated, detail-oriented, and able to work both independently and collaboratively in a dynamic research environment.

The pay range for this position is $45.00 - $50.00/hr.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:

• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave)

This is a fully onsite position in Cambridge, MA.

This position is anticipated to close on Oct 31, 2025.