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Executive Director, Portfolio Lead, Global Discovery Chemistry

Bristol Myers Squibb

Company : Bristol Myers Squibb

Location : Cambridge, MA, 02141

Posted Date : 28 October 2025

Job Type : Full Time

Category : Management

Occupation : Executive Director

Job Details

Portfolio Lead/Executive Director, Global Discovery Chemistry

Working with Us Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

The Portfolio Lead/Executive Director, Global Discovery Chemistry (GDC), plays a critical leadership role in setting the strategic direction, integration, and successful execution of chemistry programs. This position supports one or more therapeutic areas and advances Bristol Myers Squibb's mission to improve the lives of patients through science. As a key member of the GDC Leadership Team, the individual in this role will significantly influence the overall discovery chemistry strategy at BMS.

This leader is responsible for overseeing teams within Global Discovery Chemistry, guiding their efforts to identify, prioritize, and develop innovative drug molecules. These efforts are expected to meet rigorous scientific standards and align with the company's portfolio objectives. The role includes leading both matrix and direct-report teams, cultivating a culture of collaboration and accountability focused on achieving scientific milestones and delivering impactful solutions.

Additionally, the Portfolio Lead/Executive Director collaborates closely with functional leaders throughout Research and Development. This involves providing essential leadership in molecular invention, managing resources, and leveraging technology to maximize the value of the global discovery chemistry pipeline. To succeed in this position, the candidate must demonstrate a vision for scientific excellence, a collaborative mindset, and the ability to inspire teams to reach ambitious goals in a dynamic and evolving environment.

Key Responsibilities

  • Provide strategic leadership and oversee the portfolio delivery of multiple discovery chemistry programs, ensuring they are aligned with organizational objectives and consistently produce high-quality, differentiated small molecule drugs.
  • Manage site operations for Global Discovery Chemistry team at the Cambridge, MA location, upholding organizational standards and ensuring that scientific initiatives are carried out efficiently. This includes promoting a productive work environment and supporting local teams in meeting strategic goals.
  • Act as a mentor to leaders, teams, and scientists within the organization, encouraging the adoption and implementation of AI/ML tools and other innovative technologies that accelerate the development of new medicines.
  • Promote collaboration and accountability within both matrix and line teams to ensure the delivery of impactful scientific results.
  • Ensure strategic alignment and progress across one or more therapeutic areas within the BMS portfolio.

Qualifications & Experience

  • A Ph.D. in organic or medicinal chemistry with a minimum of 15 years of relevant post-graduate experience in the pharmaceutical or biotechnology sectors.
  • Demonstrated success in leading medicinal chemistry teams that have advanced innovative drug candidates to clinical development. Experience with one or more chemical modalities such as antibody-drug conjugates (ADCs), monovalent or bivalent protein degraders, oligonucleotides, and/or macrocyclic peptides is preferred.
  • Proven ability to drive scientific excellence and inspire cross-functional teams to achieve ambitious objectives.
  • Experience working collaboratively with diverse stakeholders in complex research and development environments.
  • Strong leadership and communication skills, combined with a collaborative and forward-thinking approach.

If you find a role that excites you but your experience doesn't perfectly match the description, we encourage you to apply. You might be closer than you think to work that could transform your career and your life.

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Years holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

With a single vision as inspiring as Transforming patients lives through science, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

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